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Synfacts 2008(6): 0564-0564  
DOI: 10.1055/s-2008-1072603
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (-)-Erinacine E

Contributor(s): Philip Kocienski, Arndt W. Schmidt
H. Watanabe, M. Nakada*
Waseda University, Tokyo, Japan
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Publication History

Publication Date:
21 May 2008 (online)

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Significance

(-)-Erinacine E was isolated in 1996 from Henricium erinaceum, which is used in Chinese folk medicine, and by fermentation from a different Henricium species. The 5-6-7 tricyclic cyathane skeleton is the common feature of the structurally related striatals and other erinacines.