An Iron-Catalyzed Direct Approach to Amides from Benzyl Azides via C–C Bond Cleavage

Abstract

A novel iron-catalyzed transformation of benzyl azides to give the corresponding amides via C–C bond cleavage under mild reaction conditions is developed. This method provides a new synthetic tool for the construction of amides and the opportunity to accomplish C–C functionalization under mild conditions.

Key words

C–C bond cleavage - azides - amides - rearrangement

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