Planta Medica

Issue 11/12 · July 2016

Editorial
919
Hamburger, Matthias; Potterat, Olivier; Wolfender, Jean-Luc; Queiroz, Emerson:
Special Issue dedicated to Prof. Dr. Dres. h. c. mult. Kurt Hostettmann

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Perspectives
920
Gertsch, Jürg:
The Metabolic Plant Feedback Hypothesis: How Plant Secondary Metabolites Nonspecifically Impact Human Health
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Reviews
930
Fürer, Karin; Simões-Wüst, Ana Paula; von Mandach, Ursula; Hamburger, Matthias; Potterat, Olivier:
Bryophyllum pinnatum and Related Species Used in Anthroposophic Medicine: Constituents, Pharmacological Activities, and Clinical Efficacy
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942
Ríos, José-Luis; Onteniente, María; Picazo, Dolores; Montesinos, María-Carmen:
Medicinal Plants and Natural Products as Potential Sources for Antiparkinson Drugs
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952
Recio, Mari-Carmen; Giner, Rosa-María; Máñez, Salvador:
Immunmodulatory and Antiproliferative Properties of Rhodiola Species
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Biological and Pharmacological Activity
Original Papers
961
Ansel, Jean-Luc; Lupo, Elise; Mijouin, Lily; Guillot, Samuel; Butaud, Jean-François; Ho, Raimana; Lecellier, Gaël; Raharivelomanana, Phila; Pichon, Chantal:
Biological Activity of Polynesian Calophyllum inophyllum Oil Extract on Human Skin Cells

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967
Dioum, Mbaye Diaw; Seck, Matar; Silvestre, Virginie; Planchat, Aurélien; Loquet, Denis; Lohard, Steven; Barille-Nion, Sophie; Remaud, Gerald S; Robins, Richard J; Tea, Illa:
A Ring-D-Seco-Tetranortriterpenoid from Seeds of Carapa procera Active against Breast Cancer Cell Lines

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973
Schäfer, S.; Salcher, S.; Seiter, M.; Ranninger, C.; Möst, M.; Obexer, P.; Huber, C. G.; Ausserlechner, M. J.; Schwaiger, S.; Stuppner, H.:
Characterization of the XIAP-Inhibiting Proanthocyanidin Fraction of the Aerial Parts of Ephedra sinica

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986
Santana, Ana I.; Vila, Roser; Cañigueral, Salvador; Gupta, Mahabir P.:
Chemical Composition and Biological Activity of Essential Oils from Different Species of Piper from Panama

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992
Tsoukalas, Michail; Muller, Christian D.; Lobstein, Annelise; Urbain, Aurélie:
Pregnane Glycosides from Cynanchum marnierianum Stimulate GLP-1 Secretion in STC-1 Cells
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1000
Wedler, Jonas; Rusanov, Krasimir; Atanassov, Ivan; Butterweck, Veronika:
A Polyphenol-Enriched Fraction of Rose Oil Distillation Wastewater Inhibits Cell Proliferation, Migration and TNF-α-Induced VEGF Secretion in Human Immortalized Keratinocytes

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1009
Kratz, Jadel M.; Mair, Christina E.; Oettl, Sarah K.; Saxena, Priyanka; Scheel, Olaf; Schuster, Daniela; Hering, Steffen; Rollinger, Judith M.:
hERG Channel Blocking Ipecac Alkaloids Identified by Combined In Silico – In Vitro Screening

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1016
Santomauro, Francesca; Donato, Rosa; Sacco, Cristiana; Pini, Gabriella; Flamini, Guido; Bilia, Anna Rita:
Vapour and Liquid-Phase Artemisia annua Essential Oil Activities against Several Clinical Strains of Candida

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Pharmacokinetic Investigations
Original Papers
1021
Jähne, Evelyn A.; Eigenmann, Daniela E.; Sampath, Chethan; Butterweck, Veronika; Culot, Maxime; Cecchelli, Roméo; Gosselet, Fabien; Walter, Fruzsina R.; Deli, Mária A.; Smieško, Martin; Hamburger, Matthias; Oufir, Mouhssin:
Pharmacokinetics and In Vitro Blood-Brain Barrier Screening of the Plant-Derived Alkaloid Tryptanthrin

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1030
Mair, Christina E.; de Miranda Silva, Carolina; Grienke, Ulrike; Kratz, Jadel M.; Carreño, Fernando; Zimmermann, Estevan Sonego; de Araújo, Bibiana Verlindo; Dalla Costa, Teresa; Rollinger, Judith M.:
Pharmacokinetics of hERG Channel Blocking Voacangine in Wistar Rats Applying a Validated LC-ESI-MS/MS Method

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Natural Product Chemistry and Analytical Studies
Original Papers
1039
Guccione, Clizia; Bergonzi, Maria Camilla; Piazzini, Vieri; Bilia, Anna Rita:
A Simple and Rapid HPLC-PDA MS Method for the Profiling of Citrus Peels and Traditional Italian Liquors

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1046
Nilsu, Thanasan; Thorroad, Sakornrat; Ruchirawat, Somsak; Thasana, Nopporn:
Squarrosine A and Pyrrolhuperzine A, New Lycopodium Alkaloids from Thai and Philippine Huperzia squarrosa

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1051
Azzollini, Antonio; Favre-Godal, Quentin; Zhang, Jiaozhen; Marcourt, Laurence; Ebrahimi, Samad Nejad; Wang, Shuqi; Fan, Peihong; Lou, Hongxiang; Guillarme, Davy; Queiroz, Emerson Ferreira; Wolfender, Jean-Luc:
Preparative Scale MS-Guided Isolation of Bioactive Compounds Using High-Resolution Flash Chromatography: Antifungals from Chiloscyphus polyanthos as a Case Study

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1058
Avula, Bharathi; Sagi, Satyanarayanaraju; Wang, Yan-Hong; Wang, Mei; Gafner, Stefan; Manthey, John A.; Khan, Ikhlas A.:
Liquid Chromatography-Electrospray Ionization Mass Spectrometry Analysis of Limonoids and Flavonoids in Seeds of Grapefruits, Other Citrus Species, and Dietary Supplements

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1070
Brieudes, Vincent; Angelis, Apostolis; Vougogiannopoulou, Konstantina; Pratsinis, Harris; Kletsas, Dimitris; Mitakou, Sofia; Halabalaki, Maria; Skaltsounis, Leandros A.:
Phytochemical Analysis and Antioxidant Potential of the Phytonutrient-Rich Decoction of Cichorium spinosum and C. intybus

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1079
Ndunda, Beth; Langat, Moses K.; Mulholland, Dulcie A.; Eastman, Harry; Jacob, Melissa R.; Khan, Shabana I.; Walker, Larry A.; Muhammad, Ilias; Kerubo, Leonidah O.; Midiwo, Jacob O.:
New ent-Clerodane and Abietane Diterpenoids from the Roots of Kenyan Croton megalocarpoides Friis & M. G. Gilbert

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1087
Fossen, Torgils; Yahorau, Aleh; Yahorava, Sviatlana; Raharinjato, Fanja; Razafimahefa, Solofoniaina; Rasoanaivo, Philippe; Wikberg, Jarl E. S.:
New Polyfunctional Phragmalin Limonoids from Neobeguea mahafalensis

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1096
Ren, Yulin; Benatrehina, P. Annécie; Muñoz Acuña, Ulyana; Yuan, Chunhua; Chai, Hee-Byung; Ninh, Tran Ngoc; Carcache de Blanco, Esperanza J.; Soejarto, Djaja D.; Kinghorn, A. Douglas:
Isolation of Bioactive Rotenoids and Isoflavonoids from the Fruits of Millettia caerulea

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1105
Skalicka-Woźniak, Krystyna; Mroczek, Tomasz; Walasek, Magdalena; Głowniak, Kazimierz:
Efficient Isolation of Dihydropyranocoumarins and Simple Coumarins from Mutellina purpurea Fruits

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1110
Alsabil, Khaled; Suor-Cherer, Sorphon; Koeberle, Andreas; Viault, Guillaume; Lavaud, Alexis; Temml, Veronika; Waltenberger, Birgit; Schuster, Daniela; Litaudon, Marc; Lorkowski, Stefan; de Vaumas, René; Helesbeux, Jean-Jacques; Guilet, David; Stuppner, Hermann; Werz, Oliver; Seraphin, Denis; Richomme, Pascal:
Semisynthetic and Natural Garcinoic Acid Isoforms as New mPGES-1 Inhibitors

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1117
Prawat, Hunsa; Mahidol, Chulabhorn; Kaweetripob, Wirongrong; Intachote, Pakamas; Pisutjaroenpong, Somchai; Ruchirawat, Somsak:
Cytotoxic Steroidal Glycosides from the Whole Plant of Calamus acanthophyllus

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1122
Jiang, He Zhong; Tan, Rui; Jiao, Rui Hua; Deng, Xin Zhao; Tan, Ren Xiang:
Herpecaudin from Herpetospermum caudigerum, a Xanthine Oxidase Inhibitor with a Novel Isoprenoid Scaffold

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1128
Zhang, Jiao-Zhen; Qiao, Ya-Nan; Li, Lin; Wang, Yong-Jie; Li, Yi; Fei, Xie; Zhou, Jin-Chuan; Wang, Xiao; Fan, Pei-Hong; Lou, Hong-Xiang:
ent-Eudesmane-Type Sesquiterpenoids from the Chinese Liverwort Chiloscyphus polyanthus var. rivularis

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1134
Chang, Jennifer B.; Lane, Majella E.; Yang, Min; Heinrich, Michael:
A Hexa-Herbal TCM Decoction Used to Treat Skin Inflammation: An LC-MS-Based Phytochemical Analysis

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Planta Medica

Special Issue dedicated to Prof. Dr. Dres. h. c. mult. Kurt Hostettmann

The Metabolic Plant Feedback Hypothesis: How Plant Secondary Metabolites Nonspecifically Impact Human Health

Bryophyllum pinnatum and Related Species Used in Anthroposophic Medicine: Constituents, Pharmacological Activities, and Clinical Efficacy

Medicinal Plants and Natural Products as Potential Sources for Antiparkinson Drugs

Immunmodulatory and Antiproliferative Properties of Rhodiola Species

Biological Activity of Polynesian Calophyllum inophyllum Oil Extract on Human Skin Cells

A Ring-D-Seco-Tetranortriterpenoid from Seeds of Carapa procera Active against Breast Cancer Cell Lines

Characterization of the XIAP-Inhibiting Proanthocyanidin Fraction of the Aerial Parts of Ephedra sinica

Chemical Composition and Biological Activity of Essential Oils from Different Species of Piper from Panama

Pregnane Glycosides from Cynanchum marnierianum Stimulate GLP-1 Secretion in STC-1 Cells

A Polyphenol-Enriched Fraction of Rose Oil Distillation Wastewater Inhibits Cell Proliferation, Migration and TNF-α-Induced VEGF Secretion in Human Immortalized Keratinocytes

hERG Channel Blocking Ipecac Alkaloids Identified by Combined In Silico – In Vitro Screening

Vapour and Liquid-Phase Artemisia annua Essential Oil Activities against Several Clinical Strains of Candida

Pharmacokinetics and In Vitro Blood-Brain Barrier Screening of the Plant-Derived Alkaloid Tryptanthrin

Pharmacokinetics of hERG Channel Blocking Voacangine in Wistar Rats Applying a Validated LC-ESI-MS/MS Method

A Simple and Rapid HPLC-PDA MS Method for the Profiling of Citrus Peels and Traditional Italian Liquors

Squarrosine A and Pyrrolhuperzine A, New Lycopodium Alkaloids from Thai and Philippine Huperzia squarrosa

Preparative Scale MS-Guided Isolation of Bioactive Compounds Using High-Resolution Flash Chromatography: Antifungals from Chiloscyphus polyanthos as a Case Study

Liquid Chromatography-Electrospray Ionization Mass Spectrometry Analysis of Limonoids and Flavonoids in Seeds of Grapefruits, Other Citrus Species, and Dietary Supplements

Phytochemical Analysis and Antioxidant Potential of the Phytonutrient-Rich Decoction of Cichorium spinosum and C. intybus

New ent-Clerodane and Abietane Diterpenoids from the Roots of Kenyan Croton megalocarpoides Friis & M. G. Gilbert

New Polyfunctional Phragmalin Limonoids from Neobeguea mahafalensis

Isolation of Bioactive Rotenoids and Isoflavonoids from the Fruits of Millettia caerulea

Efficient Isolation of Dihydropyranocoumarins and Simple Coumarins from Mutellina purpurea Fruits

Semisynthetic and Natural Garcinoic Acid Isoforms as New mPGES-1 Inhibitors

Cytotoxic Steroidal Glycosides from the Whole Plant of Calamus acanthophyllus

Herpecaudin from Herpetospermum caudigerum, a Xanthine Oxidase Inhibitor with a Novel Isoprenoid Scaffold

ent-Eudesmane-Type Sesquiterpenoids from the Chinese Liverwort Chiloscyphus polyanthus var. rivularis

A Hexa-Herbal TCM Decoction Used to Treat Skin Inflammation: An LC-MS-Based Phytochemical Analysis