Abstracts (HTML) List of Authors

Dabere, O

Hepatitis B virus (HBV) DNA integration is not driven by viral proteins

Dabiri, Y

Site-specific Smad3 linker region phosphorylation as a marker in cholangiocarcinoma

Dächert, C

Tackling the HCV Life Cycle with Mathematical Modeling – Decoding the Enigma
Activation of the interferon response by HCV is mediated by MDA5 and potentiated by LGP2

Dahl, A

Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control
Loss of zonation in end stage liver disease revealed by in situ omics
The RNA binding protein HuR is a master regulator of hepatic-lipid homeostasis

Dahmen, U

Cellular and nuclear hepatocyte ploidy represent a repository in regenerating livers

Dalvi, P

Metabolic Changes upon Inhibition of the Lysine-Specific-Demethylase-1 (LSD1) in Hepatocellular Carcinoma
Epigenitic Modifications by the Histone Demethylase LSD1 in Hepatic Stellate Cells Contribute to Liver Fibrosis

Damm, G

Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control
Loss of zonation in end stage liver disease revealed by in situ omics

Dammermann, W

Anti-HEV humoral immunity in long term travellers from Germany to tropical regions in Asia and Africa

Dandri, M

The levels of circulating pgRNA strongly correlate with intrahepatic pgRNA and cccDNA amounts both in HBV mono-infected and in HBV/HDV coinfected humanized mice
T-Cell Receptor Grafting allows Control of Hepatitis B Virus Infection
Analysis of liver biopsies reveals a strong intrahepatic reduction of HDV and inflammatory markers after treatment with Myrcludex B in combination with Tenofovir in chronic HBV/HDV infected patients
Differential response of culture-derived HDV-1 and HDV-3 strains to peg-IFNα treatment in human liver chimeric mice despite strong ISG induction

Daniel, S

Evaluation des Stellenwertes der cfDNA-Serumkonzentration für portale Hypertension bei Leberzirrhose

Datz, B

A simple clinical score to predict survival in patients with hepatocellular carcinoma

Datz, C

Variants in TM6SF2, PNPLA3 and PCSK7 are risk factors for the development of cirrhosis in people with genetic haemochromatosis
Whole metabolome profiling identifies the combination of an eicosanoid, a bile acid and an androgen as a highly accurate marker of liver fibrosis in patients with non-alcoholic fatty liver disease
Carriage of HSD17B13 rs72613567TA is associated with a reduced risk for developing hepatocellular carcinoma in patients with alcohol-related cirrhosis

Davis, RJ

Combined function of c-Jun N-terminal kinases in hepatocytes protects mice from fibrosis development during cholestatic liver injury
Hepatocytic c-Jun N-terminal kinases (JNK) protect against cystogenesis in NEMO-deficient mice

Dejardin, E

Mechanisms of Lymphotoxin-beta Receptor Agonization induced upregulation of the anti-HBV host restriction factor APOBEC3B

De Keizer, B

Prostate-specific membrane antigen expression in hepatocellular carcinoma: potential use for prognosis and diagnostic imaging

De la Torre, C

Mutation of PRSS23 promotes HCC development via activation of AKT/PI3K/mTOR signaling

Demir, M

No significant impact of HCC surveillance on overall mortality – data from a tertiary referral center in Germany

Denk, A

Delirium – of outstanding relevance for the interprofessional team on an intensive care unit with focus on hepatology

Denk, G

Akalzämische Vitamin-D-Analoga zeigen antifibrotische Effekte in vitro in hepatischen Sternzellen und in vivo im CCl4-Mausmodell
Accumulating bile salts promote liver fibrosis in cholestasis: in vivo evidence in a mouse model

De Ponti, A

Hepatic Progenitor Cells/Oval Cells Mediate Pro-inflammatory Responses upon Liver Injuries

de Toni, E

Akalzämische Vitamin-D-Analoga zeigen antifibrotische Effekte in vitro in hepatischen Sternzellen und in vivo im CCl4-Mausmodell

Deutschmann, K

Upregulation of TGR5 (Gpbar1) in macrophages protects mice from lipopolysaccharide and Listeria monocytogenes-induced liver damage
Role of the bile acid receptor TGR5 (GPBAR1) in cholangiocarcinoma (CCA)

Dewidar, B

Jagged-1 upregulation in stressed hepatocytes is crucial for liver regeneration
Simultaneous isolation of parenchymal and non-parenchymal cells from healthy and diseased mice liver

Dietrich, P

The potent modulator of cholesterol biosynthesis insulin-induced gene 1 (INSIG1) is a novel hypoxia-regulated tumor suppressor in hepatocellular carcinoma
Variation of the expression of different Histone deacetylases (HDACs) and the functional effects of HDAC-inhibitors in hepatocellular carcinoma
Expression and function of neuroblastoma RAS viral oncogene homolog (NRAS) in hepatocellular carcinoma
Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma

Dikopoulos, N

Baseline patient characteristics of the German multicentric prospective real-world NAFLD cohort: The Fatty Liver Assessment in Germany (FLAG) study

Ding, H

Transcription factor TRIM33 controls liver progenitor cell towards hepatocyte differentiation through synergizing with phosphorylated Smad2/3 in liver cirrhosis

Djouder, N

Platelet GPIba is a mediator and potential interventional target for NASH and subsequent liver cancer

Dobrikova, K

Targeting mitochondrial dysfunction can restore antiviral activity of NK cells in HIV/HCV coinfection

Doleschel, D

Modulation of hepatocyte-specific c-Jun N-terminal kinase 2 (JNK2) during chronic liver disease using gene silencing

Dombrowski, F

Proteomic analysis of clear cell foci in the human liver identifies differential expression of Starch-Binding Domain-Containing Protein 1 (STBD1)
Hepatocellular clear cell foci in ChREBP knockout and wild type mice after intraportal pancreatic islet transplantation – a long time experiment

Donakonda, S

Foxo1-activity controls effector function of CXCR6+CD8+ T cells and prevents liver immune pathology during viral hepatitis and non-alcoholic steatohepatitis
Liver-resident memory CD8+ T cells in chronic viral infection exhibit a unique transcriptional signature and are not terminally exhausted
Development of liver-resident memory CD8+ T cells in acute-resolving and chronic viral infection of the liver

Dong, S

A targeted screen to identify relevant oncogenes in RAS activated liver cancer

Dooley, S

Glutamine deprivation link impaired metabolism to ERK pathway activation and drug resistance in liver cancer
Jagged-1 upregulation in stressed hepatocytes is crucial for liver regeneration
Simultaneous isolation of parenchymal and non-parenchymal cells from healthy and diseased mice liver
Maintenance of functional hepatocellular polarity determines recovery in acute-on-chronic liver failure
A mouse model of chronic liver disease progression and acute-on-chronic liver failure
Cellular and nuclear hepatocyte ploidy represent a repository in regenerating livers
CYP2E1 recovery is associated with a pericentral fibrosis pattern after repeated CCl4 insults
Aged Abcb4-/- mice upon acute sublethal chemical insult recapitulate features of acute-on-chronic liver failure in patients
ECM1 is a gatekeeper that restrains TGF-β activation to maintain liver homeostasis and prevent fibrogenesis
Altered Fgf21 response in alcohol induced “Acute-on-chronic liver injury” (ACLI) model
Transcription factor TRIM33 controls liver progenitor cell towards hepatocyte differentiation through synergizing with phosphorylated Smad2/3 in liver cirrhosis
Liver cell type specific discrimination of TGF-beta signaling and outcome in vitro and in vivo
Site-specific Smad3 linker region phosphorylation as a marker in cholangiocarcinoma
Differential effect of TGF-β family members on proliferation and migration in primary liver cancer
PRRX1 cooperate with ZEB1/ZEB2 in hepatocellular carcinoma

Dormann, C

Simultaneous isolation of parenchymal and non-parenchymal cells from healthy and diseased mice liver

Dow, LE

Genetically flexible murine organoids for mechanistic and functional modeling of cholangiocarcinoma

Drasdo, D

A mouse model of chronic liver disease progression and acute-on-chronic liver failure
CYP2E1 recovery is associated with a pericentral fibrosis pattern after repeated CCl4 insults

Drebber, U

Lipid droplets and associated proteins in viral hepatitis

Drenth, JPH

Three years of Obeticholic Acid (OCA) Therapy Results in Histological Improvements in Patients with Primary Biliary Cholangitis: Further Analysis of the POISE Biopsy Substudy

Dries, V

Lipid droplets and associated proteins in viral hepatitis

Dröge, C

A Novel, Cell-Based Assay Allows Direct Measurement of Bile Salt Transport and Serves as Diagnostic Tool for Antibody-Induced BSEP Deficiency (AIBD)

Dropmann, A

Simultaneous isolation of parenchymal and non-parenchymal cells from healthy and diseased mice liver
Site-specific Smad3 linker region phosphorylation as a marker in cholangiocarcinoma

Drucker, E

Protumorigenic stathmin expression in liver cancer is linked to karyopherin alpha 2-dependent import of E2F1 and TFDP1

Dudek, M

Foxo1-activity controls effector function of CXCR6+CD8+ T cells and prevents liver immune pathology during viral hepatitis and non-alcoholic steatohepatitis

Duong, S

Heterologous vaccinations induce potent specific CD8 T-cell immune responses against HCC-expressed tumor-associated antigens

Durantel, D

Mechanisms of Lymphotoxin-beta Receptor Agonization induced upregulation of the anti-HBV host restriction factor APOBEC3B

Duret, D

Steatosis and associated proteins in hepatocellular adenoma