Abstracts (HTML) List of Authors

Gaestel, M

Cytomegalovirus limits formation of intrahepatic myeloid-cell aggregates for T-cell population expansion by activating both MAPKAP kinases 2 and 3

Gagliani, N

A novel mouse model to study effects of cell-autonomous gp130 activation on infection, inflammation and tumour formation in the liver

Gaitantzi, H

How endoglin modulates the hepatocytes' response to BMP-9
Characterization of the liver phenotype of the BMP-9 knock-out mouse
Pro- and anti-tumourigenic effects of Bone morphogenetic protein 9 signaling in hepatocellular carcinoma

Gajowski, R

Wnt/β-Catenin and Hh signaling in the adult liver – an insight into distribution, interaction and regulation

Gal, FL

A rapid point-of-care device for the diagnosis of Hepatitis Delta Virus infection

Gallage, S

Platelet GPIba is a mediator and potential interventional target for NASH and subsequent liver cancer

Gallati, S

Variants in TM6SF2, PNPLA3 and PCSK7 are risk factors for the development of cirrhosis in people with genetic haemochromatosis

Galle, PR

Voluntary distance running prevents disease progression in mice with non-alcoholic fatty liver disease (NAFLD)
Exploring molecular basis of therapy response in patient derived primary liver cancer cell lines
Landscape of (epi-)genetic alterations during malignant transformation in liver cancer
Sirtuin 6 regulates innate immune responses in a syngeneic mouse model of hepatocellular carcinoma
Differential effect of TGF-β family members on proliferation and migration in primary liver cancer

Galvez, EJC

Intestinal dysbiosis drives liver disease progression via NLRP3 in the Mdr2-/- model of primary sclerosing cholangitis

Gandraß, M

A novel mouse model to study effects of cell-autonomous gp130 activation on infection, inflammation and tumour formation in the liver

Gan-Schreier, H

iPLA2b Deficiency Exacerbates an Increase of Bile Acids in the Enterohepatic Circulation by Downregulating Hepatic FXR in Mice fed with Methionine-choline-deficient Diet
Phospho- and sphingolipid metabolism is altered in hereditary hemochromatosis independent of iron content and PNPLA3 polymorphism
Liver specific-deletion of FATP4 increases hepatic triglycerides upon D8-glycerol administration: a stable isotope labelling study
iPLA2beta Deficiency in mice fed methionine-choline-deficient diet does not protect hepatic steatosis but still attenuates hepatic fatty acids, cholesterol esters, and liver enzymes
Externalization of phosphatidylethanolamine in hepatocytes from male mice is increased by iPLA2β deficiency associated with cellular oxidative stress

Gänssler, JM

Retherapie von Patienten mit chronischer Hepatitis-C Infektion nach Versagen einer Behandlung mit direct-acting agents (DAA)
Erste Erfahrung mit dem pangenotypischen Therapieregime Glecaprevir/Pibrentasvir (Maviret) zur Behandlung einer chronischen Hepatitis C Infektion

Ganzha, A

iPLA2beta Deficiency in mice fed methionine-choline-deficient diet does not protect hepatic steatosis but still attenuates hepatic fatty acids, cholesterol esters, and liver enzymes

Gargani, S

The RNA binding protein HuR is a master regulator of hepatic-lipid homeostasis

Gasparoni, G

Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control
Loss of zonation in end stage liver disease revealed by in situ omics

Gassler, N

Combined function of c-Jun N-terminal kinases in hepatocytes protects mice from fibrosis development during cholestatic liver injury

Gaßner, J

Are preoperative laboratory parameters predictive for the metabolic function of primary human hepatocytes?

Gavaghan, M

The journey of a patient with biopsy-proven non-alcoholic steatohepatitis (NASH) – results from a real-world study

Gawaz, M

Platelet GPIba is a mediator and potential interventional target for NASH and subsequent liver cancer

Gaza, A

Expression and function of neuroblastoma RAS viral oncogene homolog (NRAS) in hepatocellular carcinoma

Gebhardt, L

Lysophosphatidic acid activates peripheral glial cells

Gebhardt, R

The interactions of Hedgehog and mTor signaling in Hepatocytes
Wnt/β-Catenin and Hh signaling in the adult liver – an insight into distribution, interaction and regulation

Geffers, R

The interaction of Serum Response Factor (SRF) and ETS domain transcription factors regulate the transcription of the MDM 4 oncogene in HCC

Gehrke, N

Voluntary distance running prevents disease progression in mice with non-alcoholic fatty liver disease (NAFLD)

Geier, A

Progression of fatty liver disease to steatohepatitis and liver fibrosis is associated with altered Oncostatin M type I and type II receptor expression
Suppression of bile acid-CoA:amino acid N-acyltransferase gene expression by the interleukin-6-type cytokine Oncostatin M
The NLRP3 inflammasome rs10754558 is associated with increased serum ALT activities: analysis of a prospective NAFLD cohort
The journey of a patient with biopsy-proven non-alcoholic steatohepatitis (NASH) – results from a real-world study
A simple clinical score to predict survival in patients with hepatocellular carcinoma
Effect of selective internal radiation therapy (SIRT) in patients with unresectable primary or metastatic liver tumors on microsomal liver function by means of 13C-methacetin breath test (MBT)

Geisslinger, G

Hepatocellular autotaxin is a major source of systemic lysophosphatidic acid and regulates glucose homeostasis

Genesca, J

Bei Patienten mit homozygotem Alpha1-Antitrypsinmangel (Pi*ZZ) ist die Substitution von Alpha1-Antitrypsin mit besseren Leberparametern assoziiert

Gerardy-Schahn, R

Engaging antiviral antibodies for tumor therapy using bispecific adapter proteins

Gerbes, AL

Akalzämische Vitamin-D-Analoga zeigen antifibrotische Effekte in vitro in hepatischen Sternzellen und in vivo im CCl4-Mausmodell

Gerken, G

Low free triiodothyronine (fT3) is associated with advanced fibrosis in non-alcoholic steatohepatitis (NASH)
The Hippo signalling is induced by Toll-like receptor 4 activation and regulatory balance innate immune responses in liver cells
Auswirkung einer Binge Eating Episode auf Leberschädigung, den Gallensäuremetabolismus und Zelltodmarker
Hepatitis B virus particles activate toll-like receptor 2 signaling initial upon infection of primary human hepatocytes
Factors positively correlated with HBs seroconversion in chronic hepatitis B – a single center experience in a German cohort of 387 patients
Characteristics and outcome of 544 patients with autoimmune hepatitis (AIH) – a single centre experience
Enzymatic liver function measured by LiMAx – a reliable diagnostic tool in chronic liver disease

Gertzen, C

Role of the bile acid receptor TGR5 (GPBAR1) in cholangiocarcinoma (CCA)

Ghallab, A

Acetaminophen (APAP)-induces a dynamic response of the Hippo pathway and its effector yes-associated protein (YAP) in hepatocellular cells
A mouse model of chronic liver disease progression and acute-on-chronic liver failure

Ghamarnejad, O

Meta-analysis of the efficacy of preoperative biliary drainage in hilar cholangiocarcinoma
The effect of Pringle maneuver in surgical outcome in patients underwent extended hepatectomy

GhamarNejad, O

Liver Resection for Cholangiocarcinoma: Biological and Surgical Predictors of Outcome, Status Quo in Additive Therapy

Ghamar Nejad, O

Endocystectomy technique for surgical treatment of hepatic cystic echinococcosis

Ghennam, E

The damage of tight junction proteins in elder MDR 2-/- knockout mice: A question of cholestasis?

Giersch, K

The levels of circulating pgRNA strongly correlate with intrahepatic pgRNA and cccDNA amounts both in HBV mono-infected and in HBV/HDV coinfected humanized mice
Differential response of culture-derived HDV-1 and HDV-3 strains to peg-IFNα treatment in human liver chimeric mice despite strong ISG induction

Giesler, M

An alternative model for prediction of transplant-free survival in patients with implantation of transjugular intrahepatic portosystemic shunt (TIPS): The Freiburg risk score

Gillich, N

Activation of the interferon response by HCV is mediated by MDA5 and potentiated by LGP2

Glebe, D

Loss of the middle hepatitis B virus (HBV) surface antigen (MHBs) during interferon-alpha (PEG-IFN) treatment is associated with subsequent lower HBV replication in patients with chronic HBeAg negative hepatitis B

Gluud, LL

The CLIF-C AD-score predicts mortality in patients with non-decompensated cirrhosis

Goeppert, B

Cholangiocarcinogenesis is a developmental process driven by distinct sequential alterations of the cellular transcriptome
Protumorigenic stathmin expression in liver cancer is linked to karyopherin alpha 2-dependent import of E2F1 and TFDP1
MiRNAs involved in development of intraepithelial precursor lesions and progression to cholangiocarcinoma

Goeser, F

Human intrahepatic ILC3 may modulate hepatic stellate cell activation

Goeser, T

The damage of tight junction proteins in elder MDR 2-/- knockout mice: A question of cholestasis?
No significant impact of HCC surveillance on overall mortality – data from a tertiary referral center in Germany

Goetze, O

Effect of selective internal radiation therapy (SIRT) in patients with unresectable primary or metastatic liver tumors on microsomal liver function by means of 13C-methacetin breath test (MBT)

Gohlke, H

Role of the bile acid receptor TGR5 (GPBAR1) in cholangiocarcinoma (CCA)

Golriz, M

Meta-analysis of the efficacy of preoperative biliary drainage in hilar cholangiocarcinoma

Goltz, D

Prostate-specific membrane antigen expression in hepatocellular carcinoma: potential use for prognosis and diagnostic imaging

Gordan, J

MEK inhibition suppresses cholangiocarcinoma growth by restraining tumor cell proliferation and modulating tumor microenvironment

Gordien, E

A rapid point-of-care device for the diagnosis of Hepatitis Delta Virus infection

Görg, B

Effects of SNPs in HE-relevant genes on the development of hepatic encephalopathy in patients with liver cirrhosis
Hepatic encephalopathy is linked to alterations of autophagic flux in astrocytes caused by hyperammonemia

Gostick, E

Viral escape contributes to the failure of hepatitis D virus (HDV)-specific CD8+ T cells and drives population-level evolution of HDV

Gotter, C

Targeting mitochondrial dysfunction can restore antiviral activity of NK cells in HIV/HCV coinfection

Gottfried-Brand, D

Sirtuin 6 regulates innate immune responses in a syngeneic mouse model of hepatocellular carcinoma

Gotthardt, D

Variants in TM6SF2, PNPLA3 and PCSK7 are risk factors for the development of cirrhosis in people with genetic haemochromatosis
Carriage of HSD17B13 rs72613567TA is associated with a reduced risk for developing hepatocellular carcinoma in patients with alcohol-related cirrhosis
Biliary calprotectin, lactoferrin and dimeric pyruvate kinase after liver transplantation are markers for biliary damage and predict graft survival

Götze, O

A simple clinical score to predict survival in patients with hepatocellular carcinoma

Gould, K

Simultaneous isolation of parenchymal and non-parenchymal cells from healthy and diseased mice liver
ECM1 is a gatekeeper that restrains TGF-β activation to maintain liver homeostasis and prevent fibrogenesis

Gozdowska, J

Common variant p.D19 H of the hepatobiliary sterol transporter ABCG5/8 increases the gallstone risk and affects cholesterol homeostasis in children

Grandt, D

Varizenblutung oder Aszites: Was bewirkt den Unterschied?

Grandt, J

The CLIF-C AD-score predicts mortality in patients with non-decompensated cirrhosis

Greinert, R

Protektiver Effekt von Statinen auf die Entstehung der heptischen Enzephalopathie ist abhängig von häufigen Genvarianten

Gremse, F

An unexpected protective role for macrophages during hepatocellular carcinoma-associated cachexia

Gretz, N

Mutation of PRSS23 promotes HCC development via activation of AKT/PI3K/mTOR signaling

Grevelding, CG

Hepatozelluläre c-Jun Aktivierung durch Schistosoma mansoni Infektion im Hamster Modell und primären humanen Hepatozyten
Hepatozelluläre Aktivierung von β-Catenin und Survivin durch Schistosoma mansoni Infektion im Hamster-Modell

Grewe, I

Monocytes as a potential trigger of Th17-differentiation in primary sclerosing cholangitis (PSC)

Griffiths, WJH

Variants in TM6SF2, PNPLA3 and PCSK7 are risk factors for the development of cirrhosis in people with genetic haemochromatosis

Grimminger, P

Differential effect of TGF-β family members on proliferation and migration in primary liver cancer

Groth, S

Altered microbiota and bile acid composition in patients with primary sclerosing cholangitis

Grove, J

Carriage of HSD17B13 rs72613567TA is associated with a reduced risk for developing hepatocellular carcinoma in patients with alcohol-related cirrhosis

Grünhage, F

Quantitative trait analysis in Abcb4 deficient mice identifies Pcks9 as a potential modifier gene

Grzybek, M

The RNA binding protein HuR is a master regulator of hepatic-lipid homeostasis

Gschwendter, H

Impact of new targeted therapies on the regulation of p53-family and cell death behavior of hepatoma cells in hepatocellular carcinoma

Gschwendtner, H

Reduced mucus layer and destabilized epithelial barrier – are these the first triggers driving spontaneous bacterial peritonitis?
Recognition of bacteria by intestinal epithelial cells and regulation of p53 signaling and cell death – interactions at the epithelial interface leading to spontaneous bacterial peritonitis in liver cirrhosis

Gu, Z

Clearance of chronic HCV infection leads to an expansion of a follicular T helper cell memory phenotype in HCV-specific CD4 T cells

Guenther, V

High real-world efficacy of elbasvir/grazoprevir (EBR/GZR) in genotype 1 (GT1) infected patients with and without liver cirrhosis: results from the German Hepatitis C Registry (DHC-R)

Guha, IN

Spleen to liver stiffness ratio significantly differs between ALD and HCV and predicts disease-specific complications

Guldiken, N

In severe alcoholic hepatitis, serum transferrin predicts mortality independently of disease severity
Serum CYFRA 21 – 1 levels are elevated in advanced liver disease and associate with poor survival

Gülow, K

Reduced mucus layer and destabilized epithelial barrier – are these the first triggers driving spontaneous bacterial peritonitis?
Proliferation, migration and cell viability in hepatocellular carcinoma – what is the impact of IGFBP2?
Induction of cell death in hepatocellular carcinoma (HCC) via energy depletion
Impact of new targeted therapies on the regulation of p53-family and cell death behavior of hepatoma cells in hepatocellular carcinoma
Recognition of bacteria by intestinal epithelial cells and regulation of p53 signaling and cell death – interactions at the epithelial interface leading to spontaneous bacterial peritonitis in liver cirrhosis

Gunda, M

Macrophage-hepatocyte crosstalk modulates hepcidin under physiological oxygen levels

Guo, F

c-MYC overexpression in hepatocytes is associated with spontaneous development of non-alcoholic steatohepatitis (NASH) in mice

Gürlevik, E

Analysis of T cell exhaustion in tumor-specific CD8 T cells utilizing an orthotopic hepatocellular carcinoma mouse model

Guthke, R

Palmitic acid treatment alters expression of arachidonic-acid pathway associated genes in hepatoma cells linking fatty acids to inflammation

Guttmann, S

SERPINA1 levels dictate TTR expression in HepG2 cells