Abstracts (HTML) List of Authors

Baba, HA

The Hippo signalling is induced by Toll-like receptor 4 activation and regulatory balance innate immune responses in liver cells
Hepatitis B virus particles activate toll-like receptor 2 signaling initial upon infection of primary human hepatocytes

Backhus, J

Der Einsatz einer permanenten Aszitesdrainage bei Patienten mit therapierefraktärem Aszites bei Peritonealkarzinose und end-stage-Leberzirrhose: Vergleich des Komplikationen- und Sicherheitsprofils
Evaluation des Stellenwertes der cfDNA-Serumkonzentration für portale Hypertension bei Leberzirrhose

Backu, E

Proliferation, migration and cell viability in hepatocellular carcinoma – what is the impact of IGFBP2?

Badenhoop, K

Hepatocellular autotaxin is a major source of systemic lysophosphatidic acid and regulates glucose homeostasis

Balp, MM

The journey of a patient with biopsy-proven non-alcoholic steatohepatitis (NASH) – results from a real-world study

Bals, R

Bei Patienten mit homozygotem Alpha1-Antitrypsinmangel (Pi*ZZ) ist die Substitution von Alpha1-Antitrypsin mit besseren Leberparametern assoziiert

Banales, JM

MiRNAs involved in development of intraepithelial precursor lesions and progression to cholangiocarcinoma

Bang, C

Altered microbiota and bile acid composition in patients with primary sclerosing cholangitis

Bantel, H

Senescence of T-Cells Increases with Fibrosis Progression in Chronic Viral Hepatitis
Maintenance of functional hepatocellular polarity determines recovery in acute-on-chronic liver failure
Transcription factor TRIM33 controls liver progenitor cell towards hepatocyte differentiation through synergizing with phosphorylated Smad2/3 in liver cirrhosis

Barat, S

IL-22 and IL22-binding protein are associated with development of and mortality from acute-on-chronic liver failure (ACLF)

Baretton, G

Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control
Loss of zonation in end stage liver disease revealed by in situ omics

Barikbin, R

Interferon-γ-dependent immune responses contribute to the pathogenesis of primary sclerosing cholangitis in mice

Barreto, G

Dysregulated epigenetic factors in non-alcoholic fatty liver disease and triggered liver cancer

Bartenschlager, R

Identification of host cell factors involved in hepatitis C virus replication
Role of autophagy in hepatitis C virus replication
Hepatitis C virus inhibits IL-1β-induced IκBζ expression in a Calpain-dependent manner resulting in LCN2 suppression
Hepatitis C Virus mediates induction of CXC chemokine expression in response to the inflammatory cytokines TNFα and IL-1β
The pivotal role of target cells in modulating efficacy of antiviral CD8 T cell immunity in the liver
Lipid droplets and associated proteins in viral hepatitis
Activation of the interferon response by HCV is mediated by MDA5 and potentiated by LGP2

Bastgen, D

Varizenblutung oder Aszites: Was bewirkt den Unterschied?

Bauer, M

Functional assessment of peritoneal mucosal associated invariant T (MAIT) cells in advanced cirrhosis

Bauer, T

T-Cell Receptor Grafting allows Control of Hepatitis B Virus Infection

Baumann, S

Metabolische Wirkungen mesenchymaler Stromalzellen in der nicht-alkoholischen Steatohepatitis

Baumert, T

Clearance of chronic HCV infection leads to an expansion of a follicular T helper cell memory phenotype in HCV-specific CD4 T cells

Bazinet, M

Absence of mutations in the HBsAg “a” determinant during REP 2139 therapy validates serum HBsAg reductions observed in the REP 102 protocol
Mutations in hepatitis B virus surface antigen during therapy with nucleic acid polymer REP 2139-Ca have no influence on treatment outcome or its detection by diagnostic assays

Bazylak-Kapps, B

Hepatocyte-derived calcineurin regulates the development of hepatocellular carcinoma independent of hepatic steatohepatitis

Bechmann, L

Low free triiodothyronine (fT3) is associated with advanced fibrosis in non-alcoholic steatohepatitis (NASH)
Auswirkung einer Binge Eating Episode auf Leberschädigung, den Gallensäuremetabolismus und Zelltodmarker

Becker, D

Exploring molecular basis of therapy response in patient derived primary liver cancer cell lines
Genetically flexible murine organoids for mechanistic and functional modeling of cholangiocarcinoma

Becker, T

Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control
Loss of zonation in end stage liver disease revealed by in situ omics

Bedossa, P

Three years of Obeticholic Acid (OCA) Therapy Results in Histological Improvements in Patients with Primary Biliary Cholangitis: Further Analysis of the POISE Biopsy Substudy

Beer, B

Genetically flexible murine organoids for mechanistic and functional modeling of cholangiocarcinoma

Bender, S

Activation of the interferon response by HCV is mediated by MDA5 and potentiated by LGP2

Bendtsen, F

Collagen type IV remodeling gender-specifically predicts mortality in decompensated liver cirrhosis

Benedé-Ubieto, R

c-MYC overexpression in hepatocytes is associated with spontaneous development of non-alcoholic steatohepatitis (NASH) in mice

Bengsch, B

Metabolic programming of exhausted CD8+ T cells in chronic viral hepatitis
Phenotypic and functional differences of HBVcore- versus HBVpolymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load

Benjamin, G

Liver Resection for Cholangiocarcinoma: Biological and Surgical Predictors of Outcome, Status Quo in Additive Therapy

Berg, C

Serologische Differenzierung zwischen alkoholischer Lebererkrankung (ALD) und nicht-alkoholischer Fettlebererkrankung (NAFLD) anhand des Nachweises von IgA-Antikörpern gegen Alkoholdehydrogenase (ADH)

Berg, T

Variants in TM6SF2, PNPLA3 and PCSK7 are risk factors for the development of cirrhosis in people with genetic haemochromatosis
Whole metabolome profiling identifies the combination of an eicosanoid, a bile acid and an androgen as a highly accurate marker of liver fibrosis in patients with non-alcoholic fatty liver disease
Loss of the middle hepatitis B virus (HBV) surface antigen (MHBs) during interferon-alpha (PEG-IFN) treatment is associated with subsequent lower HBV replication in patients with chronic HBeAg negative hepatitis B
Carriage of HSD17B13 rs72613567TA is associated with a reduced risk for developing hepatocellular carcinoma in patients with alcohol-related cirrhosis

Bergen, M von

Metabolische Wirkungen mesenchymaler Stromalzellen in der nicht-alkoholischen Steatohepatitis

Berger, A

Evaluation des Stellenwertes der cfDNA-Serumkonzentration für portale Hypertension bei Leberzirrhose

Bergheim, D

Prostate-specific membrane antigen expression in hepatocellular carcinoma: potential use for prognosis and diagnostic imaging

Berkhout, L

Interferon-γ-dependent immune responses contribute to the pathogenesis of primary sclerosing cholangitis in mice

Berres, ML

Genetic deletion of the chemokine Cxcl10 diminish HCC burden in a murine liver cancer model by modulation of tumor stroma
Novel short-termed mouse model of intrahepatic cholangiocarcinoma (ICC) by orthotopic transplantation of ICC cell line in C57/B6 mice

Best, J

Low free triiodothyronine (fT3) is associated with advanced fibrosis in non-alcoholic steatohepatitis (NASH)
Auswirkung einer Binge Eating Episode auf Leberschädigung, den Gallensäuremetabolismus und Zelltodmarker

Bettinger, D

An alternative model for prediction of transplant-free survival in patients with implantation of transjugular intrahepatic portosystemic shunt (TIPS): The Freiburg risk score

Beuers, U

Accumulating bile salts promote liver fibrosis in cholestasis: in vivo evidence in a mouse model

Bidmon, HJ

Hepatic encephalopathy is linked to alterations of autophagic flux in astrocytes caused by hyperammonemia

Biedenbach, J

Voluntary distance running prevents disease progression in mice with non-alcoholic fatty liver disease (NAFLD)

Bilzer, M

High real-world efficacy of elbasvir/grazoprevir (EBR/GZR) in genotype 1 (GT1) infected patients with and without liver cirrhosis: results from the German Hepatitis C Registry (DHC-R)

Binder, H

Landscape of (epi-)genetic alterations during malignant transformation in liver cancer

Binder, M

Reshaping of the cellular signaling landscape under continuous stimulation of innate antiviral responses
Tackling the HCV Life Cycle with Mathematical Modeling – Decoding the Enigma
Activation of the interferon response by HCV is mediated by MDA5 and potentiated by LGP2

Bockmann, JH

Viral escape contributes to the failure of hepatitis D virus (HDV)-specific CD8+ T cells and drives population-level evolution of HDV
Krankheitsverständnis und Lebensqualität von Patienten mit chronischer Hepatitis B (HBV) Infektion mit und ohne antivirale Therapie
Analysis of liver biopsies reveals a strong intrahepatic reduction of HDV and inflammatory markers after treatment with Myrcludex B in combination with Tenofovir in chronic HBV/HDV infected patients

Bode, JG

Hepatitis C virus inhibits IL-1β-induced IκBζ expression in a Calpain-dependent manner resulting in LCN2 suppression
Hepatitis C Virus mediates induction of CXC chemokine expression in response to the inflammatory cytokines TNFα and IL-1β
Deletion of thrombin receptor PAR4 attenuates the development of insulin resistance and NAFLD in mouse fed high-fat diet
Cytomegalovirus limits formation of intrahepatic myeloid-cell aggregates for T-cell population expansion by activating both MAPKAP kinases 2 and 3
Hepatocytes induces properties of wound healing type and regulatory macrophages in co-cultivated BMDM

Boden, K

Hepatitis E is a frequent cause of severe acute liver injury – a tertiary referral center experience

Boettler, T

Clearance of chronic HCV infection leads to an expansion of a follicular T helper cell memory phenotype in HCV-specific CD4 T cells
Combined OX40 stimulation and PD-L1 blockade reinforce HBV-specific CD4 T cell responses
Type I Interferons promote maintenance and function of follicular T helper cells in vitro
An alternative model for prediction of transplant-free survival in patients with implantation of transjugular intrahepatic portosystemic shunt (TIPS): The Freiburg risk score

Böhm, K

Underdilation of controlled expansion transjugular intrahepatic portosystemic shunt (TIPS) preserves cardiac function and improves outcome

Böhm, S

Loss of the middle hepatitis B virus (HBV) surface antigen (MHBs) during interferon-alpha (PEG-IFN) treatment is associated with subsequent lower HBV replication in patients with chronic HBeAg negative hepatitis B

Boor, P

A mouse model of chronic liver disease progression and acute-on-chronic liver failure

Bopp, C

Hepatische Abcg5/g8-Defizienz führt zu erhöhten Cholesterinspiegeln in der Galle

Borkham-Kamphorst, E

LCN2 null mice are sensitive to endoplasmic reticulum stress and unfolded protein responses

Bosch, M

Liver-resident memory CD8+ T cells in chronic viral infection exhibit a unique transcriptional signature and are not terminally exhausted
Development of liver-resident memory CD8+ T cells in acute-resolving and chronic viral infection of the liver

Bösch, F

Akalzämische Vitamin-D-Analoga zeigen antifibrotische Effekte in vitro in hepatischen Sternzellen und in vivo im CCl4-Mausmodell

Bosserhoff, AK

Hepatic steatosis potentiates irinotecan-induced hepatocellular steatohepatitis via dysregulation of irinotecan-metabolizing enzymes
Chain length and saturation status of fatty acids significantly affect cellular injury and lipid metabolism of primary human hepatocytes
Pregnancy-associated plasma protein-A as potential novel target and serum marker for hepatic fibrosis
The potent modulator of cholesterol biosynthesis insulin-induced gene 1 (INSIG1) is a novel hypoxia-regulated tumor suppressor in hepatocellular carcinoma
Variation of the expression of different Histone deacetylases (HDACs) and the functional effects of HDAC-inhibitors in hepatocellular carcinoma
Expression and function of neuroblastoma RAS viral oncogene homolog (NRAS) in hepatocellular carcinoma
Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma

Bovensiepen, C

Visualization and analysis of inflammatory type T-cells in autoimmune hepatitis

Bowlus, CL

Three years of Obeticholic Acid (OCA) Therapy Results in Histological Improvements in Patients with Primary Biliary Cholangitis: Further Analysis of the POISE Biopsy Substudy

Branchi, V

Human intrahepatic ILC3 may modulate hepatic stellate cell activation

Brandt, EF

Genetic deletion of the chemokine Cxcl10 diminish HCC burden in a murine liver cancer model by modulation of tumor stroma
Novel short-termed mouse model of intrahepatic cholangiocarcinoma (ICC) by orthotopic transplantation of ICC cell line in C57/B6 mice

Brass, C

The journey of a patient with biopsy-proven non-alcoholic steatohepatitis (NASH) – results from a real-world study

Breitkopf-Heinlein, K

How endoglin modulates the hepatocytes' response to BMP-9
Characterization of the liver phenotype of the BMP-9 knock-out mouse
Pro- and anti-tumourigenic effects of Bone morphogenetic protein 9 signaling in hepatocellular carcinoma

Breuhahn, K

Acetaminophen (APAP)-induces a dynamic response of the Hippo pathway and its effector yes-associated protein (YAP) in hepatocellular cells
A mouse model of chronic liver disease progression and acute-on-chronic liver failure
TAZ-inactivation partly compensates the phenotype caused by YAP knockdown in livers of YAP/TAZ-deficient mice
Protumorigenic stathmin expression in liver cancer is linked to karyopherin alpha 2-dependent import of E2F1 and TFDP1

Brinz, S

Der Einsatz einer permanenten Aszitesdrainage bei Patienten mit therapierefraktärem Aszites bei Peritonealkarzinose und end-stage-Leberzirrhose: Vergleich des Komplikationen- und Sicherheitsprofils

Brodesser, S

Auswirkung einer Binge Eating Episode auf Leberschädigung, den Gallensäuremetabolismus und Zelltodmarker

Broering, R

The Hippo signalling is induced by Toll-like receptor 4 activation and regulatory balance innate immune responses in liver cells
Hepatitis B virus particles activate toll-like receptor 2 signaling initial upon infection of primary human hepatocytes

Bröker, K

Anti-HEV humoral immunity in long term travellers from Germany to tropical regions in Asia and Africa

Brooks, J

Engaging antiviral antibodies for tumor therapy using bispecific adapter proteins

Brosch, M

Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control
Whole metabolome profiling identifies the combination of an eicosanoid, a bile acid and an androgen as a highly accurate marker of liver fibrosis in patients with non-alcoholic fatty liver disease
Loss of zonation in end stage liver disease revealed by in situ omics
Wnt/β-Catenin and Hh signaling in the adult liver – an insight into distribution, interaction and regulation
The RNA binding protein HuR is a master regulator of hepatic-lipid homeostasis

Bruckmann, A

Chemerin-156 reduces liver tumor growth in vivo but has no effect on liver cell proliferation and migration

Brückner, S

Verification of 3D liver organoids from cholangiocarcinoma tissue for chemotherapeutic drug screening

Brugger, M

Interplay of caspase activation, calcium signaling and decreased mitochondria resilience enables viral clearance in the liver

Brügger, B

Identification of host cell factors involved in hepatitis C virus replication

Brüne, B

Impaired adaptive immunity is an early event in liver cirrhosis preceding acute-on-chronic liver failure
IL-22 and IL22-binding protein are associated with development of and mortality from acute-on-chronic liver failure (ACLF)

Brunner, SM

Induction of biliary epithelial wound healing and angiogenesis through IL6 in donor bile ducts after liver transplantation

Bruns, T

Serum CYFRA 21 – 1 levels are elevated in advanced liver disease and associate with poor survival
Functional assessment of peritoneal mucosal associated invariant T (MAIT) cells in advanced cirrhosis
Hepatitis E is a frequent cause of severe acute liver injury – a tertiary referral center experience
The ATG16L1 Gene Variant rs2241880 (p.T300A) Is Associated With Susceptibility to HCC In Patients with Cirrhosis

Buch, S

Variants in TM6SF2, PNPLA3 and PCSK7 are risk factors for the development of cirrhosis in people with genetic haemochromatosis
Carriage of HSD17B13 rs72613567TA is associated with a reduced risk for developing hepatocellular carcinoma in patients with alcohol-related cirrhosis

Büchetr, M

Intravenous therapy of hepatic encephalopathy with L-ornithine l-aspartate (Lola) is safe and very effective

Büchler, MW

Endocystectomy technique for surgical treatment of hepatic cystic echinococcosis

Büchter, M

Enzymatic liver function measured by LiMAx – a reliable diagnostic tool in chronic liver disease

Buck, A

Effect of selective internal radiation therapy (SIRT) in patients with unresectable primary or metastatic liver tumors on microsomal liver function by means of 13C-methacetin breath test (MBT)

Budczies, J

RSPO2 gene rearrangement – a new cancer driver in the liver

Budeus, B

Viral escape contributes to the failure of hepatitis D virus (HDV)-specific CD8+ T cells and drives population-level evolution of HDV

Buechler, C

Chemerin-156 reduces liver tumor growth in vivo but has no effect on liver cell proliferation and migration

Buechter, M

Factors positively correlated with HBs seroconversion in chronic hepatitis B – a single center experience in a German cohort of 387 patients
Characteristics and outcome of 544 patients with autoimmune hepatitis (AIH) – a single centre experience

Buettner, N

Inefficient induction of TAA-specific CD8+ T-cell responses in hepatocellular carcinoma

Buettner, R

Metabolic Changes upon Inhibition of the Lysine-Specific-Demethylase-1 (LSD1) in Hepatocellular Carcinoma

Buggisch, P

Baseline patient characteristics of the German multicentric prospective real-world NAFLD cohort: The Fatty Liver Assessment in Germany (FLAG) study

Buhl, EM

A mouse model of chronic liver disease progression and acute-on-chronic liver failure

Burkhardt, R

The RNA binding protein HuR is a master regulator of hepatic-lipid homeostasis

Buti, M

Viral escape contributes to the failure of hepatitis D virus (HDV)-specific CD8+ T cells and drives population-level evolution of HDV

Büttner, R

Epigenitic Modifications by the Histone Demethylase LSD1 in Hepatic Stellate Cells Contribute to Liver Fibrosis
MiR-198 overexpression leads to its vesicular release from hepatocellular carcinoma cells

Byrtus, A

Varizenblutung oder Aszites: Was bewirkt den Unterschied?

Byrtus, J

Varizenblutung oder Aszites: Was bewirkt den Unterschied?