DOI: 10.1055/s-00000131

Synfacts

Issue 11 · Volume 2011 · November 2011 DOI: 10.1055/s-002-22386

Synform

A100
SYNFORM ISSUE 2011/11

Synthesis of Natural Products and Potential Drugs

z1149
All PDFs of this category
1149
Synthesis of Rho-Kinase Inhibitor Y-27632
1150
Synthesis of (+)-Przewalskin B
1151
Synthesis of a γ-Secretase Modulator
1152
Formal Synthesis of Ezetimibe
1153
Synthesis of Spirastrellolide F Methyl Ester
1154
Synthesis of HSD-016
1155
Synthesis of (+)-Brevisamide
1156
Synthesis of (±)-Hapalindoles K, A, and G
1157
Synthesis of (+)-Awajanomycin
1158
Synthesis of Febuxostat, Tafamadis, and Texaline
1159
Synthesis of Cholesterol Transporter NPC1L1 Inhibitor
1160
Synthesis of (±)-Communiol E
1161
Synthesis of Synechoxanthin

Synthesis of Heterocycles

z1163
All PDFs of this category
1163
Concise Palladium-Catalyzed Synthesis of Dibenzodiazepines
1164
Synthesis of 1-Aroxyisoquinolines from Phenols and 2-Alkynylbenzaldoximes
1165
Ru-Catalyzed Heteroannulation to Indoles, Dihydroisoquinolines, and Dihydroquinolines
1166
[3+2] Cycloaddition to Pyrido[1,2-b]indazoles
1167
Ruthenium-Catalyzed Synthesis of Phthalides in Water via C-H Alkenylation
1168
One-Pot Cu-Catalyzed C-N Coupling Approach to Pyrido[1,2-a]benzimidazoles
1169
Efficient Zinc-Mediated Heteroannulation Route to 3-Amidoindoles
1170
Base-Mediated Intramolecular Aryne-Ene Cyclization
1171
Synthesis of Benzoxazinones via Palladium-Catalyzed Intramolecular C-O Coupling
1172
Copper-Catalyzed Three-Component Synthesis of Polysubstituted Pyrroles
1173
Sonogashira-Hydroamination Route to 1,2,4-Trisubstituted Pyrroles
1174
Gold-Catalyzed [3+2]-Cycloaddition Approach to 2,4,5-Trisubstituted Oxazoles
1175
Microwave-Facilitated Synthesis of Pyrimidinones
1176
Iron-Mediated Heteroannulation Route to Isochromenones
1177
Pd-Catalyzed Heteroannulation Route to 4-Aminoquinazolines via C-H Amidination

Synthesis of Materials and Unnatural Products

z1179
All PDFs of this category
1179
A Stabilized Singlet Biradical Compound
1180
Alkynes en Route to Porphyrinoides
1181
Substitute This!
1182
A Facile Route to Polycylic Aromatic Hydrocarbons
1183
‘Ticktock’ Cyclopolymerization
1184
Polyaryl Mesobenzanthrones
1185
Expanded Cyclo[8]pyrroles Made Easy
1186
C3-Symmetric Chromophores with 6,5,5-Fused Ring Systems
1187
High-Yielding Thermal [2+2] Addition to Fullerene
1188
Controlling Calixarene Size with Metal Salts: The First Brønsted-Free Synthesis
1189
Ultra-Low Bandgap Donor-Acceptor Polymers Based on Pyromellitic Diimide
1190
Conjugated Polymers via Aroyl Chloride-Alkyne Polymerization
1191
Acenaphthene-Fused Phospholes with Enhanced Electronic Properties

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z1193
All PDFs of this category
1193
Novel Ligand for Rh-Catalyzed Asymmetric Conjugate Addition
1194
Ni-Catalyzed Reductive Cycloaddition
1195
Gold-Catalyzed Enantioselective Protonation
1196
Pd-Catalyzed Enantioselective Allylic Etherizations of Oximes
1197
Tandem Catalytic Allylic Amination and [2,3]-Stevens Rearrangement of Tertiary Amines
1198
A One-Pot Synthesis of Challenging Chiral Primary Amines
1199
Copper-Catalyzed Asymmetric 1,3-Dipolar Cycloadditions
1200
Iron-Catalyzed Oxidative Kinetic Resolution of Secondary Alcohols
1201
Thermally-Induced Cycloadditions of Diazo Compounds and Alkenes
1202
Combined C-H Functionalization/Cope Rearrangement with Vinyl Ethers
1203
Enantioselective Alder-Ene Reactions towards Dihydrobenzofurans
1204
Pd-Catalyzed Chemo- and Regioselective Allylic Alkylation
1205
Silver-Catalyzed Enantioselective 1,3-Dipolar Cycloaddition
1206
Iridium-Catalyzed Asymmetric Allylations
1207
Palladium-Catalyzed Allylic C-H Oxidation
1208
3-Aminochroman Derivatives via Ruthenium-Catalyzed Asymmetric Hydrogenation
1209
New Ligands for Catalytic Asymmetric NHK Allylation of Aldehydes
1210
Yb-Catalyzed Asymmetric Conjugate Allylation of Coumarins
1211
Domino Knovenagel/Pinner/Friedel-Crafts Synthesis of Chiral Chromenes
1212
Hetero-Diels-Alder Reaction of Brassard’s Diene and Aliphatic Aldehydes
1213
Novel Phosphorus Amidite-Olefin Ligands for Allylic Alkylation of Indoles
1214
Co-Catalyzed Conjugate Addition of Alkynes to α,β-Unsaturated Ketones
1215
Use of 1,2,4-Triazolyl-1,2,3-Triazoles as Carbene Precursors
1216
Kinetic Resolution of Morita-Baylis-Hillman Adducts by 1,4-Addition
1217
Zirconium-Catalyzed Enantioselective Friedel-Crafts Alkylation of Pyrroles
1218
Tetradentate Amine Ligands for Asymmetric Friedel-Crafts Alkylations
1219
Pd-Catalyzed Asymmetric Intramolecular Arylation of α-Keto Amides
1220
One-Pot Domino Ring Opening/C-N Bond Formations
1221
Rhodium-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids
1222
Asymmetric Ene Reaction by La/Ag Heterobimetallic Cooperative Catalysis

Metal-Mediated Synthesis

z1223
All PDFs of this category
1223
Pd-Catalyzed Direct Alkynylation of Aliphatic C-H Bonds
1224
In-Promoted Approach to Synthetic Equivalents of Hydroxyacetone Enolates
1225
One-Pot Synthesis of Functionalized Arylboronic Acids
1226
CuCl-Catalyzed β-Boration of α,β-Unsaturated Carbonyl Compounds
1227
Base-Mediated Transition-Metal-Free Alkynylation of Aryl Chlorides
1228
Asymmetric Allylic Substitution
1229
Chiral C(sp³) Boronate Building Blocks
1230
γ-Selective Cross-Coupling of Allylic Silanolate Salts
1231
Synthesis of Multialkylated Olefins through Carbozirconation and Coupling
1232
Ti-Mediated Coupling of Amines with Grignard Reagents
1233
Oxidation of Silyl Enol Ethers with Metal Nitrites
1234
CuCl2-Mediated Chlorocyclization and Oxidative Aromatization Cascade
1235
Lithium Cuprate Ion Pairs as a Key to Control Diastereoselectivity
1236
CuCF3 Aromatic Trifluoromethylating Agents
1237
Ag-Mediated Caryl-OCF3 Bond Formation
1238
Trifluoromethylation of Aromatic Isoxazoles

Organo- and Biocatalysis

z1239
All PDFs of this category
1239
Catalytic Enantioselective Oxaziridination
1240
Asymmetric Synthesis of Spirooxindoles
1241
Thiourea-Catalyzed Intramolecular [5+2] Cycloadditions
1242
Desymmetrization of Cyclohexadienones via Cinchonine-Derived Thiourea
1243
Synthesis of Aryl Alkyl Sulfides by γ-Addition of Aryl Thiols to Allenoates
1244
α-Alkylation of Aldehydes by Oxidative Coupling with Molecular Oxygen
1245
Phosphoramide-Catalyzed Michael Addition of Oxindoles to Nitroolefins
1246
Electrophilic Reactivities of Photo-Generated α,β-Unsaturated Iminium Ions
1247
Catalytic Enantioselective Desymmetrization of meso-Diamines

Polymer-Supported Synthesis

z1249
All PDFs of this category
1249
Silane Oxidation Catalyzed by Carbon Nanotube-Gold Nanohybrids
1250
Oxidation of Alcohols with PMO-Supported Oxo-Vanadium Schiff Base
1251
Silica-Supported Polyimidazolium Pd Catalysts for Suzuki-Miyaura Coupling
1252
Denitrogenative Deuteration of Solid-Supported Triazenes
1253
Suzuki-Miyaura Coupling in Water with Pd@CSP
1254
Synthesis of Unsymmetrical Sulfides with CuO Nanoparticles
1255
Polyethylene Oligomer Supported Olefin Metathesis Catalysts
1256
Reduction of Nitro Compounds with N2H4˙H2O Using Fe3O4 Nanoparticles
1257
A Recyclable Polystyrene-Supported Gold(I) Catalyst
1258
Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles with Silica-Bonded PPSA
1259
Copper Nanoparticles on Activated Carbon for Click Chemistry
1260
A Polymeric Bimetallic Catalyst for
N-Alkylation of Amines with Alcohols
1261
Transfer Hydrogenation with Immobilized Wilkinson’s Catalyst
1262
Borylation of Aryl Halides with Silica-SMAP/Pd

Addenda and Errata

1263
Fe-Catalyzed Phenanthrene Synthesis via [4+2] Benzannulation
1263
Palladium-Catalyzed C-H Activation Induced Enantioselective Route to Fused Indolines
1264
Dysprosium(III) Triflate Catalyzed Aza-Piancatelli Rearrangement
1264
Organocatalytic Enantioselective Fluorocyclizations