DOI: 10.1055/s-00000025

Hormone and Metabolic Research

Issue 01 · Volume 47 · January 2015 DOI: 10.1055/s-004-28282 New Insights Into Islet Biology and Islet Replacement

Editorial

1
Bornstein, S. R.; Amiel, S. A.; Rubino, F.; Mingrone, G.; Kamvissi, V.; Solimena, M.; Bonifacio, E.; Jones, P.; Schwarz, P.; Birkenfeld, A. L.; Behrens, A.; Barthel, A.; Lechler, R.; Peakman, M.: Creating a “Transcampus” in Diabetes Research Between King’s College London and the Technische Universität Dresden: Update on Islet Biology and Transplantation

Endocrine Care

4
Ludwig, B.; Reichel, A.; Kruppa, A.; Ludwig, S.; Steffen, A.; Weitz, J.; Bornstein, S. R.: Islet Transplantation at the Dresden Diabetes Center: Five Years’ Experience
9
Byrne, M. L.; Hopkins, D.; Littlejohn, W.; Beckford, R.; Srinivasan, P.; Heaton, N.; Amiel, S. A.; Choudhary, P.: Outcomes for Adults with Type 1 Diabetes Referred with Severe Hypoglycaemia and/or Referred for Islet Transplantation to a Specialist Hypoglycaemia Service

Review

16
Marathe, C. S.; Drogemuller, C. J.; Marathe, J. A.; Loudavaris, T.; Hawthorne, W. J.; O’Connell, P. J.; Radford, T.; Kay, T. W. H.; Horowitz, M.; Coates, P. T.; Torpy, D. J.: Islet Cell Transplantation in Australia: Screening, Remote Transplantation, and Incretin Hormone Secretion in Insulin Independent Patients

Endocrine Care

24
Evron, Y.; Zimermann, B.; Ludwig, B.; Barkai, U.; Colton, C. K.; Weir, G. C.; Arieli, B.; Maimon, S.; Shalev, N.; Yavriyants, K.; Goldman, T.; Gendler, Z.; Eizen, L.; Vardi, P.; Bloch, K.; Barthel, A.; Bornstein, S. R.; Rotem, A.: Oxygen Supply by Photosynthesis to an Implantable Islet Cell Device
Supporting Information

Review

31
Reichart, B.; Niemann, H.; Chavakis, T.; Denner, J.; Jaeckel, E.; Ludwig, B.; Marckmann, G.; Schnieke, A.; Schwinzer, R.; Seissler, J.; Tönjes, R. R.; Klymiuk, N.; Wolf, E.; Bornstein, S. R.: Xenotransplantation of Porcine Islet Cells as a Potential Option for the Treatment of Type 1 Diabetes in the Future

Endocrine Research

36
Kourtzelis, I.; Ferreira, A.; Mitroulis, I.; Ricklin, D.; Bornstein, S. R.; Waskow, C.; Lambris, J. D.; Chavakis, T.: Complement Inhibition in a Xenogeneic Model of Interactions Between Human Whole Blood and Porcine Endothelium

Commentary

43
Rahmig, S.; Bornstein, S. R.; Chavakis, T.; Jaeckel, E.; Waskow, C.: Humanized Mouse Models for Type 1 Diabetes Including Pancreatic Islet Transplantation

Endocrine Care

48
Theil, A.; Wilhelm, C.; Guhr, E.; Reinhardt, J.; Bonifacio, E.: The Relative Merits of Cord Blood as a Cell Source for Autologous T Regulatory Cell Therapy in Type 1 Diabetes

Endocrine Research

56
Richardson, C. C.; To, K.; Foot, V. L.; Hauge-Evans, A. C.; Carmignac, D.; Christie, M. R.: Increased Perinatal Remodelling of the Pancreas in Somatostatin-Deficient Mice: Potential Role of Transforming Growth Factor-Beta Signalling in Regulating Beta Cell Growth in Early Life
64
Drynda, R.; Peters, C. J.; Jones, P. M.; Bowe, J. E.: The Role of Non-Placental Signals in the Adaptation of Islets to Pregnancy
Supporting Information

Immediate Interest

72
Zhao, M.; Choudhary, P.; Srinivasan, P.; Tang, H.; Heaton, N.; Fung, M.; Barthel, A.; Bornstein, S. R.; Amiel, S. A.; Huang, G. C.: Modification of Human Islet Preparation: An Effective Approach to Improve Graft Outcome After Islet Transplantation?

Endocrine Research

78
King, A. J. F.; Clarkin, C. E.; Austin, A. L. F.; Ajram, L.; Dhunna, J. K.; Jamil, M. O.; Ditta, S. I.; Ibrahim, S.; Raza, Z.; Jones, P. M.: ALK5 Inhibition Maintains Islet Endothelial Cell Survival but does not Enhance Islet Graft Revascularisation or Function

Mini Review

84
Kamvissi, V.; Salerno, A.; Bornstein, S. R.; Mingrone, G.; Rubino, F.: Incretins or Anti-Incretins? A New Model for the “Entero-Pancreatic Axis”

Erratum

e1
Bornstein, S. R.; Amiel, S. A.; Rubino, F.; Mingrone, G.; Kamvissi, V.; Solimena, M.; Bonifacio, E.; Jones, P.; Schwarz, P.; Birkenfeld, A. L.; Behrens, A.; Barthel, A.; Lechler, R.; Peakman, M.: Creating a “Transcampus” in Diabetes Research Between King’s College London and the Technische Universität Dresden: Update on Islet Biology and Transplantation