Thieme E-Books & E-Journals - Planta Medica / Issue

IL1

Gustafson, KR: Mining the extensive chemical diversity of the NCI natural products repository for new agents that can target HIV

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IL2

Spivak, AM; Bosque, A; Martins, L; Planelles, V: Ingenol 3,20 dibenzoate efficiently reactivates latent HIV

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IL3

Rai, PP; Matainaho, T; Barrows, LR: Medicinal plants used by traditional medicine practitioners for the treatment of HIV/AIDS and related conditions in Papua New Guinea

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IL4

Chatterjee, S; Abeykoon, GA; Chen, JS: Oxylipin total synthesis uncovers stereochemistry-dependent conformations of masked diols

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IL5

Maio, WA: The taumycin A macrocycle: Asymmetric total synthesis and revision of relative stereochemistry

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IL6

May, J; Shih, JL; Nguyen, TS; Le, P; Vallakati, R; Huynh, C; Tran, T; Jansone-Popova, S; Lundy, BJ: Synthetic discoveries from polycyclic natural products

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IL7

Pierce, JG; Shymanska, NV; Edwards, GA: Marine natural products synthesis as a driving force for chemical and biological discovery

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IL8

Poulsen, TB: Total syntheses of rakicidin A and BE-43547A1

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IL9

Ibrahim, AA; Lopez, AM; Stockdill, JL: Enabling reactivity of neutral aminyl radicals in polycyclic heterocycle synthesis

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IL10

van der Donk, W: Biosynthesis of cyclic peptide antibiotics

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IL11

Eustáquio, AS; Janso, JE; Ratnayake, AS; Chang, LP; O'Donnell, CJ; Koehn, FE: Spliceostatin biosynthesis in Burkholderia spp.

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IL12

Zechel, DL: A cure for baldness and cryptic biosynthesis in Streptomyces calvus

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IL13

Kleigrewe, K; Almaliti, J; Yuheng Tian, I; Kinnel, RB; Korobeynikov, A; Monroe, EA; Duggan, BM; Di Marzo, V; Sherman, DH; Dorrestein, PC; Gerwick, L; Gerwick, WH: Discovery of novel chlorinated acyl amides from a marine cyanobacterium using integrated technologies

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IL14

Blagg, BSJ: Natural product inspired HSP90 inhibitors

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IL15

Horgen, FD: Advances in the validation of TRPM7 as a drug target using natural products – Update on waixenicin A

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IL16

Runyon, S; Rogawski, M; Gee, K; Goeders, N; Schmoutz, C: Development of novel neuroactive steroids for the potential treatment of Neurological Disorders

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IL17

Tidgewell, K; Tanvir Ahmed, K; Lax, N; Kolber, B: Panamanian marine cyanobacterial extracts with in vivo activity in models of anxiety and depression

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IL18

Balunas, MJ: Functional and biosynthetic analyses of secondary metabolites in host-microbe symbioses

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IL19

Miller, IJ; Weyna, T; Mlot, C; Fong, SS; McPhail, K; Lim-Fong, G; Kwan, JC: Integrated de novo metagenomics and metatranscriptomics to study natural products and microbial ecology in situ

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IL20

Lane, AL; James, E: Biosynthesis and ecological functions of diketopiperazine natural products from marine actinomycetes

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IL21

Rowley, D; Zhao, W; Yuan, T; Dao, C; Sohn, S; Gomez Chiarri, M; Seeram, N; Nelson, DR: Mechanisms of microbe-microbe-host interactions in a probiont-pathogen-bivalve model

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IL22

Sneed, JM; Harrison, SJ; Houk, LJ; Paul, VJ: Macroalgae may interrupt important cues for coral larval settlement

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IL23

Anderson, J; Anderson, Y; Diyabalanage, T: Paving the way with actives for skincare

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IL24

Wen Chen, C: Ergothioneine, the amazing amino acid

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IL25

Gruber, JV: From the berry to the barrier: Development of natural products for skin and hair care

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IL26

Wright, G: Biotransformation of anticancer drugs by human and environmental microbiomes

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IL27

Balskus, EP: Gut reactions: Natural products and the human microbiota

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IL28

Turnbaugh, PJ: Food, drugs, and bugs: A metagenomic view of pharmacology

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IL29

Powell, R: Historical aspects of antitumor compounds from plants, including homoharringtonine (Omacetaxine Mepesuccinate, SynriboTM)

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IL30

Kingston, DGI: Development of Taxol® as an anticancer drug

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IL31

Mooberry, SL: North American plants remain an excellent source for compounds with anticancer potential

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IL32

Newman, DJ; Cragg, GM: Are natural products isolated from plants, products of epi- and/or endo-phytic microbial interactions with/within the host?

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IL33

Muriel, C: HDAC inhibitors for cancer chemoprevention

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IL34

Shulaev, V; Jones, MD; Sturtevant, D; Chapman, KD; Isaac, G: Global lipidomics profiling of cotton seed oil genotypes using CO2-based chromatography coupled to mass spectrometry

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IL35

Suh, N: Natural tocopherol mixtures as promising cancer preventive agents

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IL36

Dietz, BM; Dunlap, TL; Hajirahimkhan, A; Wang, S; Dong, H; Simmler, C; Phansalkar, R; Ramos Alvarenga, RF; Chen, SN; Nikolic, D; van Breemen, RB; Pauli, GF; Bolton, JL: Can women's health botanicals prevent estrogen carcinogenesis?

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IL37

Hoeppner, DJ; Chenoweth, J; Kim, SK; Jaishankar, A; Wang, Y; Olivares, N; Seo, S; Stein-O'Brien, G; Colantuoni, C; McKay, R: Pluripotent stem cell colonies provide a developmental landscape for pharmacogenomic drug discovery

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IL38

Tekwani, BL; Chaurasiya, ND; Shukla, S; Muhammad, I; Walker, LA: Neurotrophic and neuritogenic drug leads from natural products: A combined in vitro assay for evaluation of cell viability and NGF-stimulated neuritic outgrowth in neuroscreen 1 cells

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IL39

Risinger, AL; Du, L; Robles, A; Sarkar, P; Perez, A; King, JB; Dybdal-Hargreaves, N; Dai, W; O'Keefe, B; Cichewicz, RH; Mooberry, SL: Utilizing differential cytotoxicity screening to identify lead compounds for rare adult and pediatric tumors

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IL40

Vizcaino, MI; Trautman, E; Engel, P; Shine, E; Crawford, JM: Discovering and deciphering the pathogenic and probiotic activities from the bacterial colibactin pathway

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IL41

Lopanik, NB: Interactions between the marine bryozoan Bugula neritina, its endosymbiont, and symbiont-produced bryostatins

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IL42

Donia, MS: Small-molecule-mediated interactions in complex microbial communities

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IL43

Haygood, M; Altamia, M; Elshahawi, S; Han, A; Lin, Z; Betcher, M; O'Connor, R; Sandy, M; Trinidade-Silva, A; Butler, A; Schmidt, E; Concepcion, G; Distel, D: Versatile bacterial symbionts of shipworms contribute to wood digestion, fix nitrogen and produce secondary metabolites

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IL44

Fenical, W: Challenges and successes in the development of natural product drugs

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IL45

Carter, GT: Measures of success in translational research

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IL46

Castor, TP: Development of Zindol® through multi-center clinical trial for chemotherapy induced nausea and vomiting

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IL47

Littlefield, BA: Discovery and development of eribulin, a macrocyclic ketone analog of halichondrin B, for treatment of advanced breast cancer

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IL48

Butler, MS: Natural products in clinical trials: Current state of play and future directions

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IL49

Fuchs, JR: Development and optimization of the phyllanthusmin class of arylnaphthalene lignan natural products

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IL50

Riley, AP; Prisinzano, TE: Synthesis of both enantiomers of the meta,meta-bridged diarylheptanoid Myricanol

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IL51

Boger, DL: Vinblastine: Synthetic and mechanistic studies

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IL52

Kelleher, NL: Metabologenomics: Discovery of new natural products and their biosynthetic gene clusters by genome-informed metabolomics

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IL53

Schirle, M: Mass spectrometry-based chemoproteomics for target deconvolution of bioactive natural products

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IL54

Yu, K; Patel, D; Qiao, L; Isaac, G; Traub, J; Yuk, J: State of art analytical technologies to solve natural products challenges

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IL55

Pan, N; Rao, W; Liu, R; Kothapalli, NR; Burgett, AW; Yang, Z: The single-probe mass spectrometry for single cell analysis and biological tissue imaging

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IL56

Schroeder, FC: Comparative metabolomics reveals a natural combinatorial library and a xylopyranose-based nucleoside in nematodes

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IL57

Owen, J: Contemporary strategies for targeted discovery and transcriptional activation of natural product biosynthetic gene clusters

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IL58

Williams, G: Harnessing the promiscuity of natural product biosynthesis: A platform for engineering pathways with new specificities

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IL59

Challis, GL: Manipulation of actinobacterial transcriptional regulation to discover new specialized metabolites

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IL60

Oberlies, NH: Endophytic fungi of medicinal herbs: Basic science and source of new drug leads

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IL61

Gunatilaka, AAL; Kithsiri Wijeratne, EM; Xu, YM; Bashyal, BP; Luo, J; Mafezoli, J; Oliveira, MCF; Hoffman, AM; Espinosa-Artiles, P; Liu, MX; Franzblau, SG; Whitesell, L: Exploring plant and lichen-associated microbial diversity for discovery of small-molecule bioactive agents

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IL62

Stadler, M: Biologically active secondary metabolites from epiphytic and endophytic fungi

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IL63

Pye, CR; Bertin, MJ; Lokey, RS; Gerwick, WH; Linington, RG: Natural products: Are we close to the end?

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IL64

Pye, C; Lokey, RS: Interrogating cyclic peptide natural products from an ADME perspective: Beyond cyclosporine A.

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IL65

Craik, DJ; Wang, C; Poth, A: Pharmaceutical applications of cyclotides

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IL66

Yudin, AK: Peptide macrocycles: From structural studies to oral bioavailability

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