Synfacts
Issue 01 · January 2011
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SYNFORM
ISSUE 2011/01
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Synthesis of Natural Products and Potential Drugs
z1
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0001
Synthesis of PA-824
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0002
Synthesis of (+)-Dictyosphaeric Acid A
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0003
Synthesis of PRC200-SS
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0004
Synthesis of (-)-Thespesone
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0005
Synthesis of Lactonamycin
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0006
Synthesis of (-)-Communesin F
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0007
Synthesis of Oseltamivir
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0008
Synthesis of (-)-Spongidepsin
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0009
Synthesis of Cortistatins A, J, K and L
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0010
Synthesis of Rhazinilam
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0011
Synthesis of a γ-Secretase Inhibitor
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0012
Synthesis of ACT-178882 (MK-1597)
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0013
Synthesis of LY503430
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Synthesis of Heterocycles
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0015
Benzofurans, Indoles, and Isoquinolones via Castro-Stephens and Heck Reactions
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0016
Palladium-Catalyzed Synthesis of 1,3,4-Benzotriazepines and Indazoles
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0017
Palladium-Catalyzed Annulation Route to 6
H
-Benzo[
c
]chromenes
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0018
Substituted Indolizines via a Multicomponent 1,3-Dipolar Cycloaddition Strategy
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0019
Synthesis of 4
H
-Chromenes by an Enantio-selective Oxa-Michael-Aldol Reaction
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0020
Regioselective Synthesis of 2-Alkoxyfurans from Cyclopropenyl Carboxylates
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0021
Metal-Free Synthesis of 1,4-Disubstituted Carbazoles from Sulfonylindoles
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0022
Horner-Wadsworth-Emmons Reagent as 1,3-Dipolar Cycloaddition Precursor
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0023
Cyclization of Zincated Homoallylamino Nitriles to Methanopyrrolidines
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0024
Synthesis of Pyrroles by [3+2] Cycloaddition of α-Diazo Oxime Ethers with Alkenes
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0025
Metal/Amine Cooperative Catalysis. Heteroannulation Route to Quinolines
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0026
1,3-Diaryl Isobenzofurans from Arylboronic Acids and
ortho
-Keto Aldehydes
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0027
Palladium-Catalyzed Heteroannulation Route to Indoles and Benzofurans
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0028
Synthesis of Dihydropyridin-4(1
H
)-ones via Wolff Rearrangement
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0029
Multicomponent Synthesis of Azaphenanthreneamides
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Synthesis of Materials and Unnatural Products
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0031
A Versatile Synthetic Method for Silaindenes
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0032
Dinaphthoporphycenes Made Easy
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0033
Polyaniline Rings
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0034
A New Method for Hypersilyl Aromatic Compounds
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0035
Oxadisilole Groups as a Benzyne Precursor and a Route to Triptycenes
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0036
Tailor-Made Donor-Acceptor Polymer for OFETs
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0037
Threaded Polythiophene
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0038
Fullerene-Fused Lactones
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0039
Stable Conjugated Disilenes
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0040
π Conjugation Through a Ferrocenothia-porphyrin Macrocycle
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0041
1,5,9-Triazacoronenes
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0042
Overcoming Insolubility Towards Thin Films
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0043
Taming the Silicon Tetraazide Beast
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0044
Double-Stranded Copper(II)
meso
-Helicates
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Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
z45
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0045
Asymmetric Propargylation of Benzaldehydes
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0046
Stereoselective [3+2] Cycloaddition of Imino Esters with Nitroalkenes
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0047
Lewis Base Catalyzed Asymmetric Selenoetherification
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0048
Synthesis of Chiral α,β-Diamino Acids Using Copper(I)/TF-BiphamPhos
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0049
Modification of BINAP Ligand has Profound Effect in Intramolecular Heck Reactions
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0050
Asymmetric Hydrophosphonylation of Ynones
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0051
Asymmetric Benzylation of 3-Aryl Oxindoles
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0052
Magnesium-Promoted N-Selective Alkylation of Amides and Carbamates
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0053
Acylsilanes as Pronucleophiles in Palladium-Catalyzed Asymmetric Allylic Alkylation
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0054
Substrate-Binding Phosphine Ligand in Enantioselective Hydroformylation
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0055
Pd-Catalyzed Asymmetric Allylic Alkylation of Heterocycles with Vinyl Aziridines
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0056
Asymmetric Hydrophosphonylation of Trifluoromethyl Ketones
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0057
Enantioselective Synthesis of
trans
-1-Alkyl-
2-Substituted Cyclopropanes
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0058
Copper-Catalyzed 1,4-Hydroboration of Coumarins with Pinacolborane
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0059
Enantioselective Cycloaddition of Nitrones with Propioloyl- and Acryloylpyrazoles
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0060
Asymmetric Dihydroxylation of Enamides to Give Quaternary Alcohols
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0061
Asymmetric Rhodium-Catalyzed Addition of Arylboronic Acids to Alkenylheteroarenes
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0062
Improved Reactivity in the Carbonyl-Ene Reaction Due to Counterion Effects
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0063
Rhodium-Catalyzed Asymmetric Hydrogenation with a P-Stereogenic Ligand
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0064
Iridium-Catalyzed Asymmetric Hydrogenation of Exocyclic Ketones, Lactones, and Lactams
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0065
Rhodium-Catalyzed Domino C-H Activation-Intramolecular Allylation of Imines
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0066
Stereoselective Enolboration of α-Trifluoro-methylpropionates
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0067
Palladium(II)-Catalyzed Asymmetric Hydrophosphination of Enones
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0068
Lewis Acid Assisted Brønsted Acid Catalyzed Asymmetric Protonation Reaction
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0069
Iron-Catalyzed Enantioselective Transfer Hydrogenation of Imines
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0070
Copper-Catalyzed 1,6-Conjugate Addition to Cyclic Dienones
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0071
Indium-Catalyzed Enantioselective Carbonyl-Ene Reaction of Trifluoropyruvate
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0072
Asymmetric Conjugate Addition to Borylalkenes
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0073
Bifunctional Catalysts for Asymmetric Conjugate Addition
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0074
Iridium-Catalyzed Enantioselective Hydrogenation of Quinoline Derivatives
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Metal-Mediated Synthesis
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0075
Pd-Ligand Controlled Cyclization for the Preparation of Heteroaromatics
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0076
Gold-Catalyzed Oxyarylation of Alkenes
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0077
Gold-Catalyzed Oxidative Coupling Reactions
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0078
Copper-Catalyzed Oxidative Trifluoromethylation of Boronic Acids
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0079
A Selective and General Palladium Catalyst for the Oxidative Heck Reaction
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0080
Selective C4 Alkylation of Pyridines Using Nickel/Lewis Acid Catalysis
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0081
Synthesis and Reactions of Amidomethyl-trifluoroborates
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0082
Arylation of α-Chiral Ketones via
Cross-Coupling of Tosylhydrazones
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0083
A New Palladium Precatalyst for the Suzuki Coupling of Unstable Boronic Acids
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0084
Iron-Catalyzed Deprotonative Alkylation of (Hetero)Arenes
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0085
Palladium-Catalyzed Carbonylative Conjugate Addition of Dialkylzinc Reagents
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0086
Substitution of Silanes with Grignard Reagents
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0087
Diamine-Free Lithiation of
N
-Boc Hetero-cycles in THF
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0088
Regio- and Stereoselective Silyl Enol Ethers
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0089
Nickel(0)-Catalyzed 1,4-Diborylation of Conjugated Dienes
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Organo- and Biocatalysis
z91
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0091
The Increased Reactivity of the Proline Carboxylate Derived Enamine
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0092
Cinchona Amino-Thiocarbamate Catalyzed Bromolactonization
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0093
Chiral Trisimidazoline Catalyzed Bromolactonization
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0094
Brønsted Acid Catalyzed Asymmetric Pinacol Rearrangement
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0095
An Umpolung Reaction of Aldehydes with Arynes
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0096
NHC-Catalyzed Michael Addition to α,β-Unsaturated Aldehydes
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0097
Synthesis of Dihydroquinolones Using a Bifunctional Thiourea Catalyst
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0098
A Simple Lewis Base Catalyst for the Asymmetric Steglich Rearrangement
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0099
Organocatalytic Construction of Polycyclic Compounds
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0100
Enantioswitching Catalysis with a Single Chiral Organocatalyst
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0101
γ-Alkylation of α-Branched Enals with Stable Carbocations
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0102
Diphosphine Oxide Catalyzed Direct Aldol Reactions
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0103
Quinidine Thiourea Catalyzed Aldol Reaction of Unactivated Ketones
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Polymer-Supported Synthesis
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0105
Asymmetric Catalysis with MOFs Prepared via Chiral Induction Effect
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0106
Coupling of Aryl Halides and Diaryl Diselenides with CuS/Fe
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0107
A One-Pot Tandem Reaction System Using Resin-Supported Peptide
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0108
Reduction of Nitrobenzenes and Oxidation of Alcohols with M-DNA
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0109
Asymmetric Arylation of Ketones with Chiral NHC Modified Fe
3
O
4
/Pd Nanoparticles
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0110
Dihydroxylation of Olefins with Dendric Osmium Complex
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0111
Photocatalytic Aerobic Oxidation of Alcohols on TiO
2
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0112
Asymmetric Transfer Hydrogenation of Ketones by Supported Rh-TsDPEN
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0113
Asymmetric Hydrogenation with MCM-41-Supported Pincer Catalysts
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0114
In Situ Coupled Oxidation Cycle Catalyzed by Reusable Platinum Catalysts
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0115
Oxidation of Alcohols by Polymeric Phosphotungstate with H
2
O
2
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0116
PANI-AgNO
3
-PTSA Salt Catalyzed Mannich Reaction
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0117
Polystyrene-Supported Chiral Auxiliary for Asymmetric Alkylation
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